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Their parties would scramble for a new nominee. Probably Pence and Harris, but not necessarily. It would be unprecedented for both parties to lose their candidates a month before the election so who knows. I mean, a ton of people have already voted, so would those votes carry over to the new nominee for that party.
There has been times in history where a candidate has died after ballots were submitted, but before they were counted. Donald Trump Virus Shirt! In at least one case the electors chose to count votes towards the dead candidates towards a party-decided candidate instead.